Office: Johnson EPS 324
B.S. – Fort Lewis College, Durango, CO – Advisor Cindy C. Browder
Ph.D. – Colorado State University, Fort Collins, CO – Advisor John L. Wood
Research Associate – Absolute Science, Lexington, MA
Research Associate – Cetek Corporation, Marlborough, MA
Research Associate – Momenta Pharmaceuticals, Cambridge, MA
Chem 112 – Introduction to Organic and Biochemistry
Chem 121-122 – General Chemistry
Chem 341 & 341L – Organic Chemistry
GENS 101 – Freshman Studies
Lauroside B (1) is a naturally occurring molecule that was first extracted from Sweet Bay Laurel in 2004. In 2011, researchers demonstrated that 1 has potent biological activity against malignant skin cancer cells, making it an attractive target for laboratory synthesis. Research in the Smith Group is focused on a synthetic route to access 1 via the intermediate synthesis of another natural product, Vomifoliol (2).
An Enantioselective Total Synthesis and Stereochemical Revision of (+)-Citrinadin B. Kong, K; Enquist, J.; McCallum, M.; Smith, G.; Matsumaru, T.; Menhaji-Klotz, E.; Wood, J. J. Am. Chem. Soc., 2013, 135 (30), pp 10890–10893.